When your travels bring you to Sioux City, our hotel's friendly staff shows you why our commitment to hospitality sets us apart. Situated conveniently off of I29 at exit 147B, the Holiday Inn Sioux City hotel's location is close to the area's major businesses and attractions. From the exhibits at the Lewis and Clark Interpretive Center to great sporting events and live entertainment at Tyson Event Center to the Sioux City Hard Rock Casino, or a show at the Historic Orpheum Theater, our city offers something enjoyable for everyone. Our location is appealing to both leisure and business travelers due to its centralized location in the heart of Sioux City. We're near Mercy Medical Center, St Luke's Hospital, June E. Nylen Cancer Center, the Sioux City Convention Center, Cargill, Morningside College, Briar Cliff University and Western Iowa Tech Community College. We also offer a convenient business center for all guests. No matter what brings you here, our winning combination of amenities ...